The James M. DuPont Meteorite Collection - C3 derivatives is malonamide semialdimine or its isomer /3-aminoacrylamide which by condensation with urea could be expected to yield uracil. Because (S-aminoacrylamide was not available to us, we tested some of the C3 compounds which are formed in the experiments with electric discharges and which are considered to be intermediates in the formation of i3-alanine. These intermediates are acrylonitrile, /3-aminopropionitrile, and /3-aminopro- pionanide. When each of these compounds was allowed to react with urea in aqueous ammonia systems at 130° C, the formation of small amounts of uracil was observed in each case.''*' Uracil was characterized by paper and ion exchange column chromatography and by ultraviolet spectrophotometry.
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The James M. DuPont Meteorite Collection - evolution, Sagan'' has calculated that the synthesized organic compounds in the contemporary atmospheres of the Jovian planets. Oro: Experimental Organic Cosmochemistry 469 and in the primitive reducing atmospheres of the terrestrial planets is of the order of 1000 g. per cm. of planetary surface. Experiments carried out by Pavlovskaya and Pasynskii"- and also in this laboratory/ have shown that several amino acids can be synthesized by irradia- tion with ultraviolet light of aqueous mixtures containing formaldehyde and ammonium salts. The synthesized amino acids, which were separated by ion exchange resins and detected by paper chromatography, include glycine, serine, alanine, and glutamic
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The James M. DuPont Meteorite Collection - a/.,"' also with the use of nitrates and ferric chloride have observed the formation of serine, aspartic acid, and asparagine from paraformaldehyde. Other amino acids formed in these experiments as detected by paper chromatography (without previous separation from other ninhydrin positive compounds by ion exchange) were glycine, alanine, and threonine and in particular C5 and Ce amino acids which are formed with difficulty in the experiments with electric discharges. These include valine, ornithine, arginine, proline, glutamic acid, histidine, leucine, isoleucine, and lysine. The above amino acids comprise essentially all the building blocks of proteins with the exception of the aromatic and sulfur containing amino acids. It would be difficult
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